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PDE7A Antikörper (Cy7)

Dieses Anti-PDE7A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PDE7A in IF (p). Geeignet für Human, Ratte und Maus.
Produktnummer ABIN1409976

Kurzübersicht für PDE7A Antikörper (Cy7) (ABIN1409976)

Target

Alle PDE7A Antikörper anzeigen
PDE7A (phosphodiesterase 7A (PDE7A))

Reaktivität

  • 36
  • 22
  • 22
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Human, Ratte, Maus

Wirt

  • 32
  • 3
  • 1
Kaninchen

Klonalität

  • 36
Polyklonal

Konjugat

  • 15
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PDE7A Antikörper ist konjugiert mit Cy7

Applikation

  • 26
  • 16
  • 10
  • 7
  • 4
  • 4
  • 3
  • 3
  • 3
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human PDE7A

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P)(1:50-200)

    Kommentare

    Exitation/Emission: 743nm/767nm

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at 4°C

    Haltbarkeit

    12 months
  • Target

    PDE7A (phosphodiesterase 7A (PDE7A))

    Andere Bezeichnung

    Pde7a

    Hintergrund

    Phosphodiesterases (PDE, also designated cyclic nucleotide phosphodiesterase) are important for the downregulation of the intracellular level of the second messenger cyclic adenosine monophosphate (cAMP) by hydrolyzing cAMP to 5'AMP. Phosphodiesterase type 3 isoforms, PDE3A and 3B, are expressed primarily in cardiovascular tissue and adipose tissue, respectively. PDE3A, is found in myocardium and platelets and PDE3B is found in lymphocytes. The PDE7A1 (HCP1) isozyme and the PDE7A2 proteins, alternate splice products of PDE7A, are highly expressed in skeletal muscle. PDE7B is most highly expressed in pancreas. The PDE family contains proteins that serve tissue-specific roles in regulation of lipolysis, glycogenolysis, myocardial contractility, and smooth muscle relaxation.


    Synonyms: HCP 1, HCP1, High affinity cAMP specic 3'5' cyclic phosphodiesterase 7A, High affinity cAMP-specic 3'', P2A, PDE 7, PDE 7A, PDE7, PDE71, PDE7A, PDE7A_HUMAN, Phosphodiesterase 7A, Phosphodiesterase isozyme 7, Phosphodiesterase7A, Rolipram insensitive phosphodiesterase type 7, TM 22, TM22, 5''-cyclic phosphodiesterase 7A.

    Pathways

    cAMP Metabolic Process
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