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ATRNL1 Antikörper (AA 501-600) (Cy7)

Dieses Anti-ATRNL1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ATRNL1 in IF (cc) und IF (p). Geeignet für Human.
Produktnummer ABIN1409550

Kurzübersicht für ATRNL1 Antikörper (AA 501-600) (Cy7) (ABIN1409550)

Target

Alle ATRNL1 Antikörper anzeigen
ATRNL1 (Attractin-Like 1 (ATRNL1))

Reaktivität

  • 18
  • 3
  • 1
Human

Wirt

  • 18
Kaninchen

Klonalität

  • 18
Polyklonal

Konjugat

  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ATRNL1 Antikörper ist konjugiert mit Cy7

Applikation

  • 12
  • 12
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 1
    AA 501-600

    Homologie

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human ATRNL1

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    ATRNL1 (Attractin-Like 1 (ATRNL1))

    Andere Bezeichnung

    ATRNL1

    Hintergrund

    Synonyms: ATRN1_HUMAN, ATRNL1, Attractin-like protein 1, KIAA0534.

    Background: ATRNL1 is a 1,379 amino acid single-pass type I membrane protein that may play a role in melanocortin signaling pathways that regulate energy homeostasis. The ATRNL1 protein contains a C-type lectin domain, a CUB domain, two EGF-like domains, six Kelch repeats, two laminin EGF-like domains and five PSI domains. ATRNL1 interacts with MC4-R in several regions known to be important in the regulation of energy homeostasis by melanocortins, such as the paraventricular nucleus of hypothalamus and the dorsal motor nucleus of the vagus. The ATRNL1 gene is conserved in dog, cow, mouse, rat, chicken, zebrafish and C. elegans, exists as two alternatively spliced isoforms and maps to human chromosome 10q25.3. Strong evidence of linkage to late-onset Alzheimer disease (LOAD) is linked to chromosome 10, which implicates a wide region and at least one disease-susceptibility locus.

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