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CADPS2 Antikörper (AA 435-510) (HRP)

CADPS2 Reaktivität: Human ELISA, IHC (fro) Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN1409528
  • Target Alle CADPS2 Antikörper anzeigen
    CADPS2 (Ca++-Dependent Secretion Activator 2 (CADPS2))
    Bindungsspezifität
    • 14
    • 1
    • 1
    • 1
    • 1
    AA 435-510
    Reaktivität
    • 18
    • 3
    • 2
    Human
    Wirt
    • 18
    Kaninchen
    Klonalität
    • 18
    Polyklonal
    Konjugat
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CADPS2 Antikörper ist konjugiert mit HRP
    Applikation
    • 13
    • 13
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CADPS2
    Isotyp
    IgG
    Top Product
    Discover our top product CADPS2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CADPS2 (Ca++-Dependent Secretion Activator 2 (CADPS2))
    Andere Bezeichnung
    CADPS2 (CADPS2 Produkte)
    Synonyme
    RGD1559440 antikoerper, A230044C21Rik antikoerper, Caps-2 antikoerper, Caps2 antikoerper, Cpd2 antikoerper, caps antikoerper, cpd2 antikoerper, zgc:110135 antikoerper, calcium dependent secretion activator 2 antikoerper, Ca2+-dependent activator protein for secretion 2 antikoerper, Ca++-dependent secretion activator 2 antikoerper, CADPS2 antikoerper, Cadps2 antikoerper, cadps2 antikoerper
    Hintergrund

    Synonyms: Cadps2, Calcium-dependent activator protein for secretion 2, Calcium-dependent secretion activator 2, CAPS2, CAPS2_HUMAN.

    Background: Calcium-dependent secretion activators (CAPS-1 and CAPS-2) are calcium-binding proteins that direct neurotransmitter and neuropeptide-filled vesicles to the cell membrane for secretory granule exocytosis. Both CAPS-1 and CAPS-2 are expressed primarily in the brain where they regulate the secretion of various substances. The CAPS proteins contain a PH domain that is essential for regulation of exocytosis, as well as regulation of phospholipid binding. Through their regulation of neurotrophin release from granule cells, CAPS proteins help to regulate cell fate during neuronal development. CAPS-1 is thought to regulate catecholamine release from neuronal cells, while CAPS-2 is thought to regulate release of both brain-derived neurotrophic factor and neurotrophin-3 from granule cells. Defects in the genes encoding CAPS-1 and CAPS-2 are implicated in impaired cerebral development and autism.

    Pathways
    Synaptic Vesicle Exocytosis
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