NAV1 Antikörper (AA 1426-1475) (Cy7)

Produktnummer ABIN1409334

Dieses Anti-NAV1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NAV1 in WB, IF (cc) und IF (p). Geeignet für Human.

Kurzübersicht für NAV1 Antikörper (AA 1426-1475) (Cy7) (ABIN1409334)

Target: NAV1 (Neuron Navigator 1 (NAV1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAV1 Antikörper ist konjugiert mit Cy7

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-NAV1 Antikörper (Cy7)

Bindungsspezifität: AA 1426-1475

Homologie: Human,Mouse,Rat,Dog,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Neuron navigator 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NAV1

Target: NAV1 (Neuron Navigator 1 (NAV1))

Andere Bezeichnung: Neuron navigator 1

Hintergrund:

Synonyms: Nav 1, Nav1, POMFIL 3, POMFIL3, Pore membrane and/or filament interacting like protein 3, Protein Steerin 1, Protein Steerin1, Steerin 1, Steerin1, unc-53 homolog 1, DKFZp781D0314, FLJ12560, FLJ14203, mNav1, NAV1_HUMAN.

Background: Neuron navigator 1 is a 1877 amino acid cytoplasmic protein that is involved in neuronal migration. Neuron navigtor 1 is widely expressed at low levels, though highest expression is found in both adult and fetal nervous tissue. Through interaction with tubulin, Neuron navigator 1 associates with a subset of mirotubule plus ends present in the growth cone. Overexpression of Neuron navigator 1 leads to microtubule bundling, whereas a reduction of its levels causes loss of directionality in the migration of pontine cell leading processes. There are seven isoforms of Neuron navigator 1 that are produced as a result of alternative splicing events.