SNAP29 Antikörper (AA 181-258) (HRP)

Produktnummer ABIN1408724

Der Kaninchen Polyklonal Anti-SNAP29-Antikörper wurde für WB, ELISA, IHC (fro) und IHC (p) validiert. Er ist geeignet, SNAP29 in Proben von Maus zu detektieren.

Kurzübersicht für SNAP29 Antikörper (AA 181-258) (HRP) (ABIN1408724)

Target: SNAP29 (Synaptosomal-Associated Protein, 29kDa (SNAP29))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNAP29 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SNAP29 Antikörper (HRP)

Bindungsspezifität: AA 181-258

Kreuzreaktivität: Maus

Homologie: Human,Rat,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SNAP29

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SNAP29

Target: SNAP29 (Synaptosomal-Associated Protein, 29kDa (SNAP29))

Andere Bezeichnung: SNAP29

Hintergrund:

Synonyms: SNAP 29, SNAP-29, SNAP29, SNP29_HUMAN, Soluble 29 kDa NSF attachment protein, Synaptosomal associated protein 29, Synaptosomal associated protein 29 kDa, Synaptosomal-associated protein 29, Vesicle membrane fusion protein SNAP 29, Vesicle membrane fusion protein SNAP29, Vesicle-membrane fusion protein SNAP-29, CEDNIK, FLJ21051.

Background: SNAP 29 is a 258 amino acid protein that localizes to the membrane and the cytoplasm, as well as to the cell junction, and contains one t-SNARE coiled-coil homology domain. Expressed in liver, heart, brain, kidney, placenta, lung, spleen, pancreas and skeletal muscle, SNAP 29 binds tightly to Syntaxins and, via this binding, is involved in membrane trafficking events. Defects in the gene encoding SNAP 29 are the cause of CEDNIK syndrome, a neurocutaneous syndrome that is associated with cerebral dysgenesis, neuropathy, ichthyosis and palmoplantar keratoderma. The gene encoding SNAP 29 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.

Gen-ID: 9342