SNAP91 Antikörper (AA 201-300) (Cy3)

Produktnummer ABIN1408539

Dieses Anti-SNAP91-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SNAP91 in WB, IF (cc) und IF (p). Geeignet für Ratte.

Kurzübersicht für SNAP91 Antikörper (AA 201-300) (Cy3) (ABIN1408539)

Target: SNAP91 (Synaptosomal-Associated Protein 91 (SNAP91))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNAP91 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-SNAP91 Antikörper (Cy3)

Bindungsspezifität: AA 201-300

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AP180

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SNAP91

Target: SNAP91 (Synaptosomal-Associated Protein 91 (SNAP91))

Andere Bezeichnung: SNAP91/AP180

Hintergrund:

Synonyms: AP 180, AP3, Assembly Protein 180 kDa, Assembly Protein AP180, CALM, Clathrin coat assembly protein, Clathrin coat assembly protein AP180, Clathrin coat associated protein AP180, DKFZp781O051, F120, KIAA0656, NP185, pp155, SNAP 91, SNAP91, 91 kDa synaptosomal associated protein, Synaptosomal associated protein 91 kD homolog, Synaptosomal associated protein 91 kDa homolog, AP180_HUMAN.

Background: Clathrin-coated pits and vesicles are assembled for receptor-mediated endocytosis through interaction with Clathrin associated protein complexes. Vesicle transport is mediated from the trans-Golgi network by the adapter complex AP-1 and from the plasma membrane by the AP-2 complex. The AP-1 and AP-2 adapter protein complexes consist of Clathrin binding Adaptin proteins (g and b1 for AP-1, a and b2 for AP-2) and two smaller subunits known as AP50 and AP17. The a and b Adaptin chains have a similar two-domain organization with C-terminal domains that vary in both sequence and length. a-Adaptin splice variants A and C display variable relative expression levels and differential distribution in different tissues. AP-3 (also designated AP180 or F1-20) is a synapse-specific Clathrin assembly protein. The protein CALM (Clathrin assembly protein lymphoid myeloid leukemia) is highly homologous to AP180 and may also be involved in Clathrin assembly.