Sapap3/Psd95bp3 (AA 201-300) Antikörper (Cy5)

Produktnummer ABIN1408438

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Sapap3/Psd95bp3 (AA 201-300) Antikörper (Cy5) (ABIN1408438)

Target: Sapap3/Psd95bp3

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails

Bindungsspezifität: AA 201-300

Homologie: Human,Mouse,Rat,Dog,Cow,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SAPAP3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Sapap3/Psd95bp3

Hintergrund:

Synonyms: DLGAP3, PSD 95/SAP90 binding protein 3, SAP90/PSD 95 associated protein 3, DAP3, Discs, large Drosophila homolog associated protein 3, Disks large associated protein 3, DLGAP3, SAPAP 3, DLGP3_HUMAN.

Background: Members of the postsynaptic density-95 (PSD-95)/SAP90 family of membrane-associated guanylate kinase (MAGUK) proteins function as multimodular scaffolds that organize protein-signaling complexes at neuronal synapses. SAPAP3 (PSD-95/SAP90-binding protein 3), also known as DLGAP3 (disks large-associated protein 3) or DAP3, is a 979 amino acid protein that belongs to the SAPAP family of PSD-95/SAP90-associated proteins. Localized to the cell junction, as well as to the peripheral membrane and the cell synapse, SAPAP3 is thought to play a role in the organization of neuronal cell signaling and synapses, and may also function as an adaptor protein, possibly linking ion channels with the cytoskeleton.