TCF12 Antikörper (AA 51-150) (HRP)

Produktnummer ABIN1407980

Der Kaninchen Polyklonal Anti-TCF12-Antikörper wurde für WB, ELISA, IHC (p) und IHC (fro) validiert. Er ist geeignet, TCF12 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für TCF12 Antikörper (AA 51-150) (HRP) (ABIN1407980)

Target: TCF12 (Transcription Factor 12 (TCF12))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCF12 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-TCF12 Antikörper (HRP)

Bindungsspezifität: AA 51-150

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Sheep,Horse,Rabbit,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TCF12

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TCF12

Target: TCF12 (Transcription Factor 12 (TCF12))

Andere Bezeichnung: TCF12/HEB

Hintergrund:

Synonyms: bHLHb20, Class B basic helix-loop-helix protein 20, DNA binding protein HTF4, DNA-binding protein HTF4, E box binding protein, E-box-binding protein, HEB, HTF4, HTF4_HUMAN, TCF-12, Tcf12, Transcription factor 12, Transcription factor HTF-4, Transcription factor HTF4.

Background: Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development includes Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes. Both homo- and hetero-oligomers of these proteins are able to distinguish very closely related E box proteins and are believed to play important roles in lineage specific gene expression.

Gen-ID: 6938

UniProt: Q99081

Pathways: SARS-CoV-2 Protein Interaktom