TMPRSS5 Antikörper (AA 161-260) (Cy7)

Produktnummer ABIN1407660

Dieses Anti-TMPRSS5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TMPRSS5 in WB, IF (cc) und IF (p). Geeignet für Human.

Kurzübersicht für TMPRSS5 Antikörper (AA 161-260) (Cy7) (ABIN1407660)

Target: TMPRSS5 (Transmembrane Protease, serine 5 (TMPRSS5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMPRSS5 Antikörper ist konjugiert mit Cy7

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-TMPRSS5 Antikörper (Cy7)

Bindungsspezifität: AA 161-260

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TMPRSS5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TMPRSS5

Target: TMPRSS5 (Transmembrane Protease, serine 5 (TMPRSS5))

Andere Bezeichnung: TMPRSS5

Hintergrund:

Synonyms: Spinesin, TMPRSS 5, TMPRSS-5, TMPRSS5, TMPS5_HUMAN, Transmembrane protease serine 5, Transmembrane protease, serine 5 spinesin, Transmembrane protease, serine 5, MGC141886, MGC148044, OTTHUMP00000238209, OTTHUMP00000238210, OTTHUMP00000238211, OTTHUMP00000238212, OTTHUMP00000238213.

Background: Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors. TMPRSS5 (transmembrane protease, serine 5), also known as spinesin, is a 457 amino acid single-pass type II membrane protein that is expressed specifically in brain and is thought to play a role in hearing. A member of the peptidase S1 family, TMPRSS5 contains one peptidase S1 domain and an SRCR domain, and is encoded by a gene that maps to human chromosome 11q23.2. Defects in the gene encoding TMPRSS5 are associated with deafness.