PAPPA2 Antikörper (AbBy Fluor® 555)
Kurzübersicht für PAPPA2 Antikörper (AbBy Fluor® 555) (ABIN1405421)
Target
Alle PAPPA2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human PAPP A2
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Isotyp
- IgG
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Applikationshinweise
- IF(IHC-P) 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- PAPPA2 (Pappalysin 2 (PAPPA2))
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Andere Bezeichnung
- PAPP A2
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Hintergrund
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Synonyms: PAPPA 2, PAPP E, PAPP-A2, PAPP-E, PAPP2_HUMAN, PAPPA 2, PAPPA2, Pappalysin 2, Pappalysin-2, PLAC3, Pregnancy associated plasma protein A2, Pregnancy associated plasma protein E1, Pregnancy-associated plasma protein A2, Pregnancy-associated plasma protein E1.
Background: Pregnancy-associated plasma protein-A (Pappalysin-1 or PAPP-A), also known as Insulin-like growth factor-dependent IGF-binding protein 4 (IGFBP4) protease, is a member of the peptidase M43B family of proteins. PAPP-A, a metalloproteinase, cleaves Insulin-like growth factor binding proteins IGFBP4 and IGFBP5, releasing bound IGF. PAPP-A is primarily expressed in septa and anchoring villi in placenta and is also expressed in pregnancy serum. Levels of PAPP-A increase throughout pregnancy. Lower levels of expression can be detected in kidney, prostate, breast, ovary and endometrial tissues. PAPP-A is a secreted protein that can form homodimers, in pregnancy serum PAPP-A may also form a heterotetramer with PRG-2.
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Gen-ID
- 60676
Target
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