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PAPPA2 Antikörper (AbBy Fluor® 555)

Der Kaninchen Polyklonal Anti-PAPPA2-Antikörper wurde für WB und IF (p) validiert. Er ist geeignet, PAPPA2 in Proben von Human, Ratte und Maus zu detektieren.
Produktnummer ABIN1405421

Kurzübersicht für PAPPA2 Antikörper (AbBy Fluor® 555) (ABIN1405421)

Target

Alle PAPPA2 Antikörper anzeigen
PAPPA2 (Pappalysin 2 (PAPPA2))

Reaktivität

  • 28
  • 18
  • 17
  • 2
  • 1
Human, Ratte, Maus

Wirt

  • 25
  • 3
Kaninchen

Klonalität

  • 25
  • 3
Polyklonal

Konjugat

  • 15
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PAPPA2 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation

  • 26
  • 12
  • 5
  • 5
  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human PAPP A2

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    PAPPA2 (Pappalysin 2 (PAPPA2))

    Andere Bezeichnung

    PAPP A2

    Hintergrund

    Synonyms: PAPPA 2, PAPP E, PAPP-A2, PAPP-E, PAPP2_HUMAN, PAPPA 2, PAPPA2, Pappalysin 2, Pappalysin-2, PLAC3, Pregnancy associated plasma protein A2, Pregnancy associated plasma protein E1, Pregnancy-associated plasma protein A2, Pregnancy-associated plasma protein E1.

    Background: Pregnancy-associated plasma protein-A (Pappalysin-1 or PAPP-A), also known as Insulin-like growth factor-dependent IGF-binding protein 4 (IGFBP4) protease, is a member of the peptidase M43B family of proteins. PAPP-A, a metalloproteinase, cleaves Insulin-like growth factor binding proteins IGFBP4 and IGFBP5, releasing bound IGF. PAPP-A is primarily expressed in septa and anchoring villi in placenta and is also expressed in pregnancy serum. Levels of PAPP-A increase throughout pregnancy. Lower levels of expression can be detected in kidney, prostate, breast, ovary and endometrial tissues. PAPP-A is a secreted protein that can form homodimers, in pregnancy serum PAPP-A may also form a heterotetramer with PRG-2.

    Gen-ID

    60676
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