TNNC1 Antikörper (pThr143) (Biotin)

Produktnummer ABIN1405087

Dieses Rabbit Polyclonal-Antikörper erkennt spezifisch TNNC1 in IHC (p). Er zeigt eine Reaktivität gegenüber Human, Mouse, Rat.

Kurzübersicht für TNNC1 Antikörper (pThr143) (Biotin) (ABIN1405087)

Target: TNNC1 (Cardiac Troponin C (TNNC1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNNC1 Antikörper ist konjugiert mit Biotin

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TNNC1 Antikörper (Biotin)

Bindungsspezifität: pThr143

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human cardiac around the phosphorylation site of Troponin I Thr143

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu TNNC1

Target: TNNC1 (Cardiac Troponin C (TNNC1))

Andere Bezeichnung: cardiac Troponin I

Hintergrund:

Synonyms: cardiac Troponin I phospho Thr143, p-cardiac Troponin I Thr143, cardiac Troponin I phospho T143, p-cardiac Troponin I T143, Cardiac troponin I, Cardiomyopathy, familial hypertrophic, 7, included, CMD1FF, CMD2A, CMH7, cTnI, Familial hypertrophic cardiomyopathy 7, MGC116817, RCM1, p-Tn1, p-Tni, TNN I3, p-TNNC 1, p-TNNC1, p-TNNI3, p-Troponin I cardiac, Troponin I cardiac muscle, Troponin I cardiac muscle isoform, Troponin I type 3 cardiac, troponin I, cardiac 3, TroponinI, TNNI3_HUMAN.

Background: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq].

Gen-ID: 7137