ANGEL2 Antikörper (AbBy Fluor® 488)

Produktnummer ABIN1404400

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ANGEL2 in WB und IF (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für ANGEL2 Antikörper (AbBy Fluor® 488) (ABIN1404400)

Target: ANGEL2 (Angel Homolog 2 (ANGEL2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANGEL2 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-ANGEL2 Antikörper (AbBy Fluor® 488)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ANGEL2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ANGEL2

Target: ANGEL2 (Angel Homolog 2 (ANGEL2))

Andere Bezeichnung: ANGEL2

Hintergrund:

Synonyms: NGE2_HUMAN, Angel homolog 2, angel2, Protein angel homolog 2.

Background: ANGEL2 is a 544 amino acid protein that belongs to the CCR4/nocturin family and exists as two alternatively spliced isoforms. The CCR4 family of proteins are 3_5_-deadenylases that function in the first step of the degradation of poly(A) mRNA. The CCR4 family most likely displays both RNA and ssDNA substrate preferences, thereby implicating a potential role in many regulatory processes. The ANGEL2 gene maps to human chromosome 1 (1q32.3), which is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. Chromosome 1 contains about 3,000 genes, and considering the great number of genes there are also a large number of diseases associated with it. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons disease, Gaucher disease and Usher syndrome are also associated with chromosome 1.

Gen-ID: 90806