NHEDC2 Antikörper (Biotin)

Produktnummer ABIN1404241

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NHEDC2 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für NHEDC2 Antikörper (Biotin) (ABIN1404241)

Target: NHEDC2 (Na+/H+ Exchanger Domain Containing 2 (NHEDC2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NHEDC2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-NHEDC2 Antikörper (Biotin)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NHEDC2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu NHEDC2

Target: NHEDC2 (Na+/H+ Exchanger Domain Containing 2 (NHEDC2))

Andere Bezeichnung: NHEDC2

Hintergrund:

Synonyms: NHA2, Mitochondrial Na+/H+ exchanger NHA2, Mitochondrial sodium/hydrogen exchanger NHA2, Na+/H+ exchanger like domain containing protein 2, Na+/H+ exchanger domain containing 2, NHE domain containing protein 2, NHE10, NHEDC 2, Sodium/hydrogen exchanger like domain containing protein 2, SL9B2_HUMAN.

Background: Na+/H+ exchangers (NHEs) catalyze the transport of Na+ in exchange for H+ across membranes in organisms and are required for numerous physiological processes. NHEDC2 (Na+/H+ exchanger-like domain-containing protein 2), also known as NHA2, is a 537 amino acid mitochondrial protein. NHEDC2 is involved in organelle volume homeostasis by catalyzing the exchange of protons for Na+ and Li+ across the inner mitochondrial membrane. Found in red blood cells, NHEDC2 is required for bone resorption activity and osteoclast differentiation. As a multi-pass membrane protein, NHEDC2 is expressed as two isoforms produced by alternative splicing events.

Gen-ID: 133308

Pathways: Proton Transport