SLC39A11 Antikörper (Biotin)

Produktnummer ABIN1403785

Produktdetails anti-SLC39A11 Antikörper (Biotin)

Target: SLC39A11 (Solute Carrier Family 39 (Metal Ion Transporter), Member 11 (SLC39A11))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC39A11 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLC39A11

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu SLC39A11

Target: SLC39A11 (Solute Carrier Family 39 (Metal Ion Transporter), Member 11 (SLC39A11))

Andere Bezeichnung: SLC39A11 (SLC39A11 Produkte)

Synonyme: 1810074D23Rik antikoerper, C17orf26 antikoerper, ZIP11 antikoerper, solute carrier family 39 member 11 antikoerper, solute carrier family 39 (metal ion transporter), member 11 antikoerper, solute carrier family 39, member 11 antikoerper, SLC39A11 antikoerper, slc39a11 antikoerper, Slc39a11 antikoerper

Hintergrund:

Synonyms: C17orf26, S39AB_HUMAN, SLC39A11, Solute carrier family 39 metal ion transporter member 11, Solute carrier family 39 member 11, Zinc transporter ZIP11, ZIP-11, ZIP11, Zrt and Irt like protein 11, Zrt- and Irt-like protein 11.

Background: Zinc is an essential cofactor that is involved in cell growth and development, as well as in protein, nucleic acid and lipid metabolism. The transport of zinc across the cell membrane is crucial for correct enzyme and overall cell function. SLC39A11 (solute carrier family 39 (metal ion transporter), member 11), also known as ZIP11 (Zrt- and Irt-like protein 11), is a 342 amino acid multi-pass membrane protein belonging to the ZIP transporter family. Expressed as multiple alternatively spliced isoforms, SLC39A11 acts as a zinc-influx transporter and is encoded by a gene located on human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes, some of which are involved in tumor suppression and in the pathogenesis of Li-Fraumeni syndrome, early onset breast cancer and a predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

Gen-ID: 201266