RPUSD2 Antikörper (AbBy Fluor® 647)

Produktnummer ABIN1403730

Dieses Anti-RPUSD2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RPUSD2 in WB und IF (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für RPUSD2 Antikörper (AbBy Fluor® 647) (ABIN1403730)

Target: RPUSD2 (RNA Pseudouridylate Synthase Domain Containing 2 (RPUSD2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPUSD2 Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-RPUSD2 Antikörper (AbBy Fluor® 647)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RPUSD2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu RPUSD2

Target: RPUSD2 (RNA Pseudouridylate Synthase Domain Containing 2 (RPUSD2))

Andere Bezeichnung: RPUSD2

Hintergrund:

Synonyms: C15orf19, C18B11, C18B11 homolog, RNA pseudouridylate synthase domain containing 2, RNA pseudouridylate synthase domain containing protein 2, RNA pseudouridylate synthase domain-containing protein 2, RPUSD 2, RPUSD-2, RUSD2_HUMAN.

Background: RPUSD2, is a 545 amino acid member of the pseudouridine synthase rluA family and is encoded by a gene that is located on chromosome 15. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and is about 3 % of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.

Gen-ID: 27079