CLLD6 Antikörper (FITC)

Produktnummer ABIN1403642

Der Kaninchen Polyklonal Anti-CLLD6-Antikörper wurde für WB und IF (p) validiert. Er ist geeignet, CLLD6 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für CLLD6 Antikörper (FITC) (ABIN1403642)

Target: CLLD6 (C13orf1) (Chromosome 13 Open Reading Frame 1 (C13orf1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLLD6 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CLLD6 Antikörper (FITC)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CLLD6/C13orf1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CLLD6

Target: CLLD6 (C13orf1) (Chromosome 13 Open Reading Frame 1 (C13orf1))

Andere Bezeichnung: CLLD6

Hintergrund:

Synonyms: Chromosome 13 open reading frame 1, Chronic lymphocytic leukemia deletion region gene 6 protein, CLL deletion region gene 6 protein, CLLD 6, CLLD6, Hypothetical protein LOC57213, SPRY7_HUMAN.

Background: CLLD6, is a 196 amino acid protein that contains one B30.2/SPRY domain. Expression of CLLD6 is found at highest levels in heart, skeletal muscle and testis, with lower levels found in thymus, peripheral blood leukocytes, lymph node and bone marrow. Existing as two alternatively spliced isoforms, CLLD6 maps to human chromosome 13, which comprises nearly 4 % of human DNA and contains about 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival.