TCF25 Antikörper (AbBy Fluor® 555)

Produktnummer ABIN1403597

Der Kaninchen Polyklonal Anti-TCF25-Antikörper wurde für WB und IF (p) validiert. Er ist geeignet, TCF25 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für TCF25 Antikörper (AbBy Fluor® 555) (ABIN1403597)

Target: TCF25 (Transcription Factor 25 (Basic Helix-Loop-Helix) (TCF25))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCF25 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-TCF25 Antikörper (AbBy Fluor® 555)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Transcription factor 25

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TCF25

Target: TCF25 (Transcription Factor 25 (Basic Helix-Loop-Helix) (TCF25))

Andere Bezeichnung: Transcription factor 25

Hintergrund:

Synonyms: FKSG26, hKIAA1049, NULP1, PRO2620, Hulp1, KIAA1049, Nuclear localized protein 1, Transcription factor 25 basic helix loop helix, TCF25_HUMAN.

Background: Transcription factor 25 acts as a transcriptional repressor. It has been shown to repress transcription of SRF in vitro and hence may play a role in heart development.Transcription factor 25, is a 676 amino acid protein that plays a role in cell death. A member of the TCF25 family, Nulp1 utilizes its C-terminus to mediate transcriptional repression of SRF in vitro, and interacts with XIAP. Nulp1 localizes primarily to the nucleus but is also found in cytosol. Widely expressed, Nulp1 is found at high levels in embryonic brain and adult heart. The gene encoding Nulp1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Gen-ID: 22980