SRF Antikörper (pSer77) (Biotin)

Produktnummer ABIN1403587

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SRF in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für SRF Antikörper (pSer77) (Biotin) (ABIN1403587)

Target: SRF (Serum Response Factor (SRF))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRF Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SRF Antikörper (Biotin)

Bindungsspezifität: pSer77

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human SRF around the phosphorylation site of Ser77

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu SRF

Target: SRF (Serum Response Factor (SRF))

Andere Bezeichnung: SRF

Hintergrund:

Synonyms: Serum Response Factor SRF phospho S77, SRF phospho Ser77, P-SRF Ser77, c fos serum response element binding factor, Serum Response Factor SRF, c fos serum response element binding transcription factor, ELK3, ERP, MCM 1, MCM-1, MCM1, OTTHUMP00000039820, SAP2, Serum response factor, SRF, SRF serum response factor c fos serum response element binding transcription factor, SRF_HUMAN.

Background: This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways, for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). [provided by RefSeq, Jul 2008].

Gen-ID: 6722