Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

TAS1R2 Antikörper (AbBy Fluor® 647)

TAS1R2 Reaktivität: Human, Ratte, Maus WB, IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 647
Produktnummer ABIN1403568
  • Target Alle TAS1R2 Antikörper anzeigen
    TAS1R2 (Taste Receptor, Type 1, Member 2 (TAS1R2))
    Reaktivität
    • 53
    • 26
    • 25
    • 5
    • 5
    • 2
    • 1
    Human, Ratte, Maus
    Wirt
    • 53
    • 1
    Kaninchen
    Klonalität
    • 54
    Polyklonal
    Konjugat
    • 17
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TAS1R2 Antikörper ist konjugiert mit AbBy Fluor® 647
    Applikation
    • 39
    • 20
    • 12
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GPR71/T1R2
    Isotyp
    IgG
    Top Product
    Discover our top product TAS1R2 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    TAS1R2 (Taste Receptor, Type 1, Member 2 (TAS1R2))
    Andere Bezeichnung
    GPR71 (TAS1R2 Produkte)
    Synonyme
    GPR71 antikoerper, T1R2 antikoerper, TR2 antikoerper, Aldh4a1 antikoerper, Gpr71 antikoerper, Tr2 antikoerper, T1r2 antikoerper, taste 1 receptor member 2 antikoerper, taste receptor, type 1, member 2 antikoerper, TAS1R2 antikoerper, Tas1r2 antikoerper
    Hintergrund

    Synonyms: GPCR TAS1R2, G protein coupled receptor 71, G-protein coupled receptor 71, GPR71, Sweet taste receptor T1R2, T1R2, TAS1R2, Taste receptor type 1 member 2, TR2, TS1R2_HUMAN, GPCR TAS1R2.

    Background: The sense of taste provides animals with valuable information about the quality and nutritional value of food. There are four widely accepted categories of taste perception, sweet, bitter, salty, and sour. A controversial fifth taste, known as umami or monosodium glutamate (MSG), has also been described. A family of G protein coupled receptors are involved in taste perception, and includes T1R, which is involved in sweet and umami taste perception, and T2R, which is involved in bitter taste perception. The T1R family consists of three members, T1R1, T1R2, and T1R3 (1-4). These proteins form heterodimers, which alters the selectivity of the subunits (1-4). The T1R2 and T1R3 heterodimer functions as a receptor for sweet taste, and recognizes several sweet-tasting molecules, such as sucrose, saccharin, dulcin, and acesulfame-K (14). The T1R1 and T1R3 heterodimer recognizes L-amino-acids to perceive umami taste. Sweet taste transduction is carried out by two pathways (2). First, sucrose and other sugars activate Gas via the T1Rs, which activates adenylyl cyclase to generate cAMP. Artificial sweeteners bind to either Gbg or Gaq coupled T1Rs to activate PLCb2 and generate IP3 and DAG. Both pathways ultimately lead to neurotransmitter release. The mouse T1R3 gene maps to chromosome 4 near the Sac locus, a primary determinant of sweet preference in mice, and it is expressed in a subset of taste cells in circumvallate, foliate, and fungiform taste papillae.

    Gen-ID
    80834
    UniProt
    Q8TE23
Sie sind hier:
Kundenservice