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MEF2B Antikörper (AbBy Fluor® 555)

Der Kaninchen Polyklonal Anti-MEF2B-Antikörper wurde für WB und IF (p) validiert. Er ist geeignet, MEF2B in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN1402901

Kurzübersicht für MEF2B Antikörper (AbBy Fluor® 555) (ABIN1402901)

Target

Alle MEF2B Antikörper anzeigen
MEF2B (Myocyte Enhancer Factor 2B (MEF2B))

Reaktivität

  • 35
  • 28
  • 19
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 33
  • 4
Kaninchen

Klonalität

  • 34
  • 3
Polyklonal

Konjugat

  • 18
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MEF2B Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation

  • 31
  • 12
  • 7
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human MEF2B

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    MEF2B (Myocyte Enhancer Factor 2B (MEF2B))

    Andere Bezeichnung

    MEF2B

    Hintergrund

    Synonyms: PRDM3, MADS box transcription enhancer factor 2, MDS1 EVI1, Mef2b, MEF2B_HUMAN, MEF-2B, myocyte enhancer factor 2B, myocyte specic enhancer factor 2B, Myocyte-specic enhancer factor 2B, RSRFR2, serum response factor like protein 2, Serum response factor-like protein 2, XMEF2.

    Background: The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells, and muscle cells. Four family members, termed MEF-2A, -2B, -2C, and -2D, arise from alternatively spliced transcripts. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5, and MRF4, are one class of identified factors. The MEF-2 family represents a second class of DNA binding regulatory proteins. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.

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