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CAF1p55 Antikörper (AbBy Fluor® 647)

Dieses Anti-CAF1p55-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CAF1p55 in WB und IF (p). Geeignet für Human, Maus und Ratte.
Produktnummer ABIN1402452

Kurzübersicht für CAF1p55 Antikörper (AbBy Fluor® 647) (ABIN1402452)

Target

CAF1p55 (CAF1) (Chromatin Assembly Factor 1 Subunit (CAF1))

Reaktivität

Human, Maus, Ratte

Wirt

  • 14
Kaninchen

Klonalität

  • 14
Polyklonal

Konjugat

  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CAF1p55 Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation

  • 14
  • 12
  • 3
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human CAF1p55

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    CAF1p55 (CAF1) (Chromatin Assembly Factor 1 Subunit (CAF1))

    Andere Bezeichnung

    CAF1p55

    Hintergrund

    Synonyms: Caf 1, CAF-1, CAF-1 P55 subunit, CAF1 p55 subunit, CAF1A, CAF1P55, chaf1b, Chromatin assembly factor 1 p55 subunit, Chromatin assembly factor 1 p60 subunit, chromatin assembly factor 1 subunit, Chromatin assembly factor I, dCAF-1, dCAF1, Human chromatin assembly factor-I p55 subunit, Nucleosome remodeling factor 55 kDa subunit, NURF 55, NURF-55, p55, Probable histone binding protein Caf1, VPRBP_HUMAN.

    Background: P55 is an extensively palmitoylated erythrocyte membrane protein, and a member of the MAGUK family. P55 also resists salt extraction, resulting in a high affinity for the plasma membrane. P55 contains a PDZ/DHR domain, a conserved SH-3 domain that appears to suppress tyrosine kinase activity of various oncoproteins, a 39-amino acid motif that binds to cytoskeletal protein 4.1R, and a guanylate kinase-like domain. Interaction with glycophorin C (GPC) and 4.1R suggests that p55 may play a role in the dynamic regulation in the erythrocyte membrane. In addition, p55 gene expression in vivo may be associated with a CpG island. P55 is constitutively expressed in K562 erythroleukemia cells during erythropoiesis and undergoes a 2-fold amplification after induction.

    Gen-ID

    9730
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