LRSAM1 Antikörper (Biotin)
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- Target Alle LRSAM1 Antikörper anzeigen
- LRSAM1 (Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1))
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser LRSAM1 Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human LRSAM1
- Isotyp
- IgG
- Top Product
- Discover our top product LRSAM1 Primärantikörper
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anti-Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1) (AA 1-723) antibody
LRSAM1 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1) (AA 1-290) antibodyLRSAM1 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1) (AA 1-30), (N-Term) antibodyLRSAM1 Reaktivität: Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB32441 unconjugated
anti-Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1) (AA 1-723) antibodyLRSAM1 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1) (Internal Region) antibodyLRSAM1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1) (AA 1-30), (N-Term) antibodyLRSAM1 Reaktivität: Human, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- LRSAM1 (Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1))
- Andere Bezeichnung
- LRSAM1 (LRSAM1 Produkte)
- Hintergrund
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Synonyms: E3 ubiquitin protein ligase LRSAM1, hTAL, Leucine rich repeat and sterile alpha mot containing protein 1, RLE, TAL, Tsg101 associated ligase, LRSM1_HUMAN.
Background: LRSAM1 is an E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivation of the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos. It selectively regulates cell adhesion molecules and plays a role in receptor endocytosis and viral budding. LRSAM1 contains a RING-type zinc finger, 5 leucine-rich repeats and 1 SAM (sterile alpha motif) domain. The coiled coil domains interact with the SB domain of TSG101. The PTAP motifs mediate the binding to UEV domains. There are 3 isoforms produced by alternative splicing.
- Gen-ID
- 90678
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