UBE2V2 Antikörper (Biotin)

Produktnummer ABIN1402369

Produktdetails anti-UBE2V2 Antikörper (Biotin)

Target: UBE2V2 (Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2V2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MMS2/EDPF1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu UBE2V2

Target: UBE2V2 (Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2))

Andere Bezeichnung: EDPF1 (UBE2V2 Produkte)

Hintergrund:

Synonyms: 1 alpha 25 dihydroxyvitamin D3 inducible, DDVit 1, DDVIT1, EDAF-1, EDAF1, EDPF-1, EDPF1, Enterocyte dferentiation associated factor EDAF 1, Enterocyte dferentiation promoting factor, Enterocyte dferentiation-associated factor 1, Enterocyte dferentiation-promoting factor 1, Methyl methanesulfonate sensitive 2, MMS 2, MMS2, MMS2 homolog, UB2V2_HUMAN, UBE2V 2, UBE2V2, Ubiquitin conjugating enzyme E2 variant 2, Ubiquitin conjugating enzyme E2v2, Ubiquitin-conjugating enzyme E2 variant 2, UEV 2, UEV2, Vitamin D3 inducible protein, Vitamin D3-inducible protein.

Background: Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.

Gen-ID: 7336

Pathways: Positive Regulation of Response to DNA Damage Stimulus