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TRIM54 Antikörper (Biotin)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TRIM54 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN1402363

Kurzübersicht für TRIM54 Antikörper (Biotin) (ABIN1402363)

Target

Alle TRIM54 Antikörper anzeigen
TRIM54 (Tripartite Motif Containing 54 (TRIM54))

Reaktivität

  • 41
  • 20
  • 19
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
Human, Maus, Ratte

Wirt

  • 36
  • 4
  • 1
Kaninchen

Klonalität

  • 37
  • 4
Polyklonal

Konjugat

  • 19
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TRIM54 Antikörper ist konjugiert mit Biotin

Applikation

  • 37
  • 17
  • 14
  • 13
  • 5
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human MURF3

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    TRIM54 (Tripartite Motif Containing 54 (TRIM54))

    Andere Bezeichnung

    MURF3

    Hintergrund

    Synonyms: MURF 3, MURF, MURF-3, MuRF3, Muscle specic RING finger protein 3, Muscle specic RING finger protein, Muscle specic RING finger protein homolog, Muscle-specic RING finger protein 3, Muscle-specic RING finger protein, Ring finger protein 30, RNF30, TRI54_HUMAN, TRIM 54, TRIM54, RNF28, Tripartite mot containing 54, tibody Tripartite mot-containing protein 54.

    Background: MuRF1, is a nuclear protein that interacts with SMT3b and the large myofibrillar protein Titin. In muscle cells, MuRF2 (RFN29) regulates gene expression and protein turnover. It localizes to the cytoplasm, but under atrophic conditions it is detected in the nucleus. MuRF2 can form oligomers with various other proteins, including Titin and Myosin. MuRF3, also designated tripartite motif-containing 54 (TRIM54) or ring finger protein 30 (RNF30), interacts with tubulin and stabilizes microtubules duing myotube formation. It is a cytoplasmic protein the localizes to the Z-lines in skeletal muscles, while MuRF2 localizes to the sarcomeric M-band in cardiomyocytes. MuRF3 shares 77 % and 65 % sequence identity with MuRF1 and MuRF2, respectively. MuRF1-3 share a conserved N-terminal RING domain and zinc-binding B-box motif, and two coiled-coil dimerization motif boxes, in their central regions.

    Gen-ID

    57159
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