PSMA6 Antikörper (Biotin)

Produktnummer ABIN1402249

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PSMA6 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für PSMA6 Antikörper (Biotin) (ABIN1402249)

Target: PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMA6 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PSMA6 Antikörper (Biotin)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Proteasome 20S alpha 6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu PSMA6

Target: PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

Hintergrund:

Synonyms: 27 kDa prosomal protein, HC2, IOTA, Macropain iota chain, Macropain subunit iota, Multicatalytic endopeptidase complex iota chain, p27K, PROS 27, PROS27, Prosomal P27K protein, Proteasome prosome macropain subunit alpha type 6, Proteasome iota chain, Proteasome subunit alpha type 1, Proteasome subunit alpha type 6, Proteasome subunit iota, PSMA6, PSA6_HUMAN.

Background: The gene encodes a 246-amino acid polypeptide containing an RNA binding motif, a putative nuclear localization signal, and phosphorylation sites. The alpha subunits comprises the outer rings of the proteasome. Some alpha subunits contain a functional nuclear localization signal, proteasomes are found in both the nuclear and cytoplasmic compartments of the cell. Alpha subunits may constitute a physical barrier that limits access of cytosolic proteins into the inner proteolytic chamber.

Gen-ID: 5687

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA