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MARCH9 Antikörper (FITC)

Der Kaninchen Polyklonal Anti-MARCH9-Antikörper wurde für WB und IF (p) validiert. Er ist geeignet, MARCH9 in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN1402178

Kurzübersicht für MARCH9 Antikörper (FITC) (ABIN1402178)

Target

Alle MARCH9 Antikörper anzeigen
MARCH9 (Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9))

Reaktivität

  • 41
  • 29
  • 20
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
Human, Maus, Ratte

Wirt

  • 38
  • 2
Kaninchen

Klonalität

  • 39
  • 2
Polyklonal

Konjugat

  • 13
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MARCH9 Antikörper ist konjugiert mit FITC

Applikation

  • 34
  • 12
  • 11
  • 3
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human MARCH9

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    MARCH9 (Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9))

    Andere Bezeichnung

    MARCH9

    Hintergrund

    Synonyms: E3 ubiquitin protein ligase MARCH9, MARCH IX, Membrane associated RING CH protein IX, membrane associated ring finger C3HC4 9, Membrane associated RING finger protein 9, RING finger protein 179, RNF179, MARH9_HUMAN.

    Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). MARCH9 (membrane-associated ring finger (C3HC4) 9), also known as RNF179, is a 346 amino acid multi-pass membrane protein that localizes to the golgi apparatus and contains one RING-CH-type zinc finger. Expressed ubiquitously, MARCH9 exists as a homodimer and functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and is thought to promote the degradation of target proteins, such as CD4 and MHC-I. Multiple isoforms of MARCH9 exist due to alternative splicing events.

    Gen-ID

    92979
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