RANBP2 Antikörper (AbBy Fluor® 350)

Produktnummer ABIN1402059

Dieses Anti-RANBP2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RANBP2 in IF (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für RANBP2 Antikörper (AbBy Fluor® 350) (ABIN1402059)

Target: RANBP2 (RAN Binding Protein 2 (RANBP2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RANBP2 Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-RANBP2 Antikörper (AbBy Fluor® 350)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RanBP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu RANBP2

Target: RANBP2 (RAN Binding Protein 2 (RANBP2))

Andere Bezeichnung: RanBP2

Hintergrund:

Synonyms: Nuclear pore complex protein Nup358, Nucleoporin 358, Nucleoporin Nup358, NUP358, P270, RAN binding protein 2, Ran-binding protein 2, RANBP2, RBP2_HUMAN, Transformation related protein 2, TRP 1, TRP 2, TRP1, TRP2, 358 kDa nucleoporin, E3 SUMO-protein ligase RanBP2.

Background: The nuclear pore complex protein, Ran-binding protein 2 (Ran BP-2 or Nup358), contains four Ran-binding domains. Ran BP-2 is a large scaffold cyclophilin-related protein expressed in photoreceptor cells. Ran BP-2 localization at cytoplasmic fibrils emanating from the nuclear pore complex and interaction with the Ran-GTPase support its role in nucleocytoplasmic transport processes. In humans, the Ran BP-2 gene is partially duplicated in a gene cluster and lies in a hot spot for recombination on chromosome 2q. This genetic heterogeneity renders further significance of this genomic region in human disease due to its possible involvement in genetically linked disorders such as juvenile nephronophthisis, congenital hepatic fibrosis and chorioretinal dysplasia.

Gen-ID: 5903

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus