KATNA1 Antikörper (AbBy Fluor® 350)

Produktnummer ABIN1401969

Dieses Anti-KATNA1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KATNA1 in WB und IF (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für KATNA1 Antikörper (AbBy Fluor® 350) (ABIN1401969)

Target: KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KATNA1 Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-KATNA1 Antikörper (AbBy Fluor® 350)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KATNA1/Katanin p60 A1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu KATNA1

Target: KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))

Andere Bezeichnung: Katanin p60 A1

Hintergrund:

Synonyms: Katanin p60 ATPase containing subunit A1, Katanin p60 ATPase-containing subunit A1, Katanin p60 subunit A1, KATNA1, KTNA1_HUMAN, p60 katanin.

Background: Microtubules are polymers of alpha and beta subunits that form the mitotic spindle and assist in the organization of membranous organelles during interphase. Katanin p60 A1, also known as KATNA1, is a 491 amino acid protein that belongs to the AAA ATPase family and is involved in microtubule regulation. Localized to the cytoplasm and to the centrosome, Katanin p60 A1 functions to sever and disassemble microtubules in an ATP-dependent manner, thus promoting the rapid reorganization of cellular microtubule arrays and playing an important role in microtubule release from the centrosome after nucleation. Katanin p60 A1, which exists as two alternatively spliced isoforms, can homooligomerize into hexameric rings whose activity is stimulated by the presence of microtubules.

Gen-ID: 11104

Pathways: Microtubule Dynamics