MUL1 Antikörper (AA 45-95) (FITC)
Kurzübersicht für MUL1 Antikörper (AA 45-95) (FITC) (ABIN1401872)
Target
Alle MUL1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 45-95
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human MUL1/RNF218
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Isotyp
- IgG
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Applikationshinweise
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FCM 1:20-100
IF(IHC-P) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))
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Andere Bezeichnung
- MUL1
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Hintergrund
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Synonyms: E3 ubiquitin-protein ligase MUL1, C1orf166, E3 ubiquitin ligase, E3 ubiquitin protein ligase MUL1, GIDE, Growth inhibition and death E3 ligase, MAPL, Mitochondrial anchored protein ligase, Mitochondrial ubiquitin ligase activator of NFKB 1, MUL1, MULAN, Putative NF kappa B activating protein 266, RING finger protein 218, RNF218, RP23-25C1.10-002, MUL1_HUMAN.
Background: E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugatin.
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Gen-ID
- 79594
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UniProt
- Q969V5
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Pathways
- Positive Regulation of Endopeptidase Activity
Target
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