MARCH10 Antikörper (AbBy Fluor® 555)

Produktnummer ABIN1401689

Der Kaninchen Polyklonal Anti-MARCH10-Antikörper wurde für WB und IF (p) validiert. Er ist geeignet, MARCH10 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für MARCH10 Antikörper (AbBy Fluor® 555) (ABIN1401689)

Target: MARCH10 (Membrane-Associated Ring Finger (C3HC4) 10, E3 Ubiquitin Protein Ligase (MARCH10))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MARCH10 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-MARCH10 Antikörper (AbBy Fluor® 555)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RNF190

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu MARCH10

Target: MARCH10 (Membrane-Associated Ring Finger (C3HC4) 10, E3 Ubiquitin Protein Ligase (MARCH10))

Andere Bezeichnung: RNF190

Hintergrund:

Synonyms: MARCH 10, MARCH X, MARCH-X, MARCH10, MARHA_HUMAN, Membrane associated ring finger C3HC4 10, Membrane associated ring finger C3HC4 10, E3 ubiquitin protein ligase, Membrane associated ring finger 10, Membrane associated RING finger protein 10, Membrane-associated RING finger protein 10, Membrane-associated RING-CH protein X, Probable E3 ubiquitin protein ligase MARCH10, Probable E3 ubiquitin-protein ligase MARCH10, Ring finger protein 190, RNF 190, RNF190.

Background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. MARCH10 (membrane-associated ring finger (C3HC4) 10), also known as RNF190 (ring finger protein 190) or MARCH-X, is an 808 amino acid protein with one RING-CH-type zinc finger domain. MARCH10 may function as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation.

Gen-ID: 162333