Protein RNF21 Antikörper (AbBy Fluor® 555)

Produktnummer ABIN1401683

Der Kaninchen Polyklonal Anti-Protein RNF21-Antikörper wurde für WB und IF (p) validiert. Er ist geeignet, Protein RNF21 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Protein RNF21 Antikörper (AbBy Fluor® 555) (ABIN1401683)

Target: Protein RNF21 (Rnf227) (RNF21 (Rnf227))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Protein RNF21 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Protein RNF21 Antikörper (AbBy Fluor® 555)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RNF21

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Protein RNF21

Target: Protein RNF21 (Rnf227) (RNF21 (Rnf227))

Andere Bezeichnung: RNF21

Hintergrund:

Synonyms: P1, Interferon Responsive Finger Protein 1, Ring Finger Protein 21, Ring finger protein 21 interferon responsive, RNF21, TRIM 34, TRIM34, Tripartite mot containing protein 34, TRI34_HUMAN.

Background: Tripartite motif-containing protein 34 (TRIM34), also known as RING finger protein 21 (RNF21) or interferon-responsive finger protein 1 (IFP1), is a 488 amino acid member of the TRIM family, also known as the RING-B-box coiled-coil (RBCC) family. Members of the RBCC family have an N-terminal RING finger, followed by one or two zinc-binding domains (B-box domains), a leucine coiled-coil region and a variable C-terminal domain. Three isoforms of TRIM34 exist as a result of alternative splicing events. Isoform 1, the most abundant isoform, is highly expressed in placenta, spleen, colon and peripheral blood leukocytes. Studies have shown that Interferon (IFN) stimulation leads to an upregulation of TRIM34. These findings suggest that TRIM34 maybe a downstream effector that mediates IFN activities.

Gen-ID: 53840