IGSF11 Antikörper (AbBy Fluor® 350)

Produktnummer ABIN1401423

Dieses Anti-IGSF11-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IGSF11 in WB und IF (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für IGSF11 Antikörper (AbBy Fluor® 350) (ABIN1401423)

Target: IGSF11 (Immunoglobulin Superfamily, Member 11 (IGSF11))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGSF11 Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-IGSF11 Antikörper (AbBy Fluor® 350)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IGSF11

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu IGSF11

Target: IGSF11 (Immunoglobulin Superfamily, Member 11 (IGSF11))

Andere Bezeichnung: IGSF11

Hintergrund:

Synonyms: brain and testis specic immunoglobin superfamily protein, BTIGSF, CXADR like 1, CXADRL1, Igsf13, immunoglobulin superfamily member 11, Immunoglobulin superfamily member 11 precursor, MGC35227, V set and immunoglobulin domain containing 3, V set and immunoglobulin domain containing protein 3, VSIG3, IGS11_HUMAN.

Background: IGSF11 is also known as BTIGSF (brain and testis-specific immunoglobulin superfamily protein) or VSIG3 (V-set and immunoglobulin domain-containing protein 3) and is a 431 amino acid protein that is expressed as three isoforms. IGSF11 is highly expressed in testis and ovary and is also expressed in brain, kidney and skeletal muscle, localized to the cellular membrane as a single-pass membrane protein. IGSF11 is an immunoglobulin with V-type and C2-type domains that function in molecular recognition. When IGSF11 is in the trans position, it plays an important role in cell-cell adhesion via both homophilic and heterophilic interactions with other molecules. These cellcell interactions are also thought to be important for neuronal cell interactions, such as neuronneuron or neuronglia interactions, which are important for the development and function of the central nervous system. In addition, IGSF11 might also be involved interactions between Sertoli cells and spermatocytes, which are important associations during spermatogenesis. The IGSF11 gene is commonly upregulated in gastric cancer and IGSF11 is highly expressed in many types of human tumors, indicating that it may be useful as a target for immunotherapy.

Gen-ID: 152404