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TRIM50 Antikörper (AbBy Fluor® 488)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TRIM50 in WB und IF (p). Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.
Produktnummer ABIN1401130

Kurzübersicht für TRIM50 Antikörper (AbBy Fluor® 488) (ABIN1401130)

Target

Alle TRIM50 Antikörper anzeigen
TRIM50 (Tripartite Motif Containing 50 (TRIM50))

Reaktivität

  • 28
  • 16
  • 15
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Ratte, Maus

Wirt

  • 28
Kaninchen

Klonalität

  • 28
Polyklonal

Konjugat

  • 10
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TRIM50 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation

  • 28
  • 12
  • 10
  • 8
  • 8
  • 5
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human TRIM50

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    TRIM50 (Tripartite Motif Containing 50 (TRIM50))

    Andere Bezeichnung

    TRIM50

    Hintergrund

    Synonyms: E3 ubiquitin ligase, E3 ubiquitin protein ligase TRIM50, TRIM50A, Tripartite mot containing protein 50, tripartite mot protein 50A, tripartite mot-containing 50A, TRI50_HUMAN.

    Background: The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM50 (tripartite motif containing 50), also known as TRIM50A or E3 ubiquitin-protein ligase TRIM50, is a 487 amino acid cytoplasmic protein that functions as an E3 ubiquitin-protein ligase. Containing one RING-type zinc finger, a B30.2/SPRY domain and a single B box-type zinc finger, TRIM50 belongs to the TRIM/RBCC family and undergoes post-translational auto-ubiquitination. TRIM50 exists as two alternatively spliced isoforms, designated TRIM50 alpha and TRIM50 beta, and has the ability to form dimers and trimers. The gene encoding TRIM50 maps to human chromosome 7, which houses over 1,000 genes, comprises nearly 5 % of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

    Gen-ID

    135892
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