Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

ZNRF2 Antikörper (Biotin)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ZNRF2 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN1401067

Kurzübersicht für ZNRF2 Antikörper (Biotin) (ABIN1401067)

Target

Alle ZNRF2 Antikörper anzeigen
ZNRF2 (Zinc and Ring Finger 2 (ZNRF2))

Reaktivität

  • 41
  • 35
  • 32
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 40
  • 1
Kaninchen

Klonalität

  • 33
  • 8
Polyklonal

Konjugat

  • 14
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ZNRF2 Antikörper ist konjugiert mit Biotin

Applikation

  • 23
  • 13
  • 6
  • 5
  • 4
  • 3
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human ZNRF2

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    ZNRF2 (Zinc and Ring Finger 2 (ZNRF2))

    Andere Bezeichnung

    ZNRF2

    Hintergrund

    Synonyms: E3 ubiquitin-protein ligase ZNRF2, Protein Ells2, RING finger protein 202, Zinc/RING finger protein 2, Znrf2, ZNRF2_HUMAN.

    Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). ZNRF2 (zinc and ring finger 2), also known as RNF202, is a 242 amino acid peripheral membrane protein that contains one RING-type zinc finger and localizes to the lysosome, as well as the endosome and the cell junction. Expressed at high levels in brain tissue, ZNRF2 is thought to function as an E3 ubiquitin-protein ligase that may be involved in the establishment and maintenance of neuronal transmission and plasticity. Upon DNA damage, ZNRF2 is subject to phosphorylation, probably by ATR or ATM.

    Gen-ID

    223082

    Pathways

    Synaptic Membrane
Sie sind hier:
Chat with us!