ATAD3A Antikörper (Biotin)

Produktnummer ABIN1400887

Produktdetails anti-ATAD3A Antikörper (Biotin)

Target: ATAD3A (ATPase Family, AAA Domain Containing 3A (ATAD3A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATAD3A Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATAD3A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu ATAD3A

Target: ATAD3A (ATPase Family, AAA Domain Containing 3A (ATAD3A))

Andere Bezeichnung: ATAD3A (ATAD3A Produkte)

Hintergrund:

Synonyms: AAA-ATPase TOB3, ATAD3B, ATAD3C, Atad3a, ATPase family AAA domain containing protein 3A, ATPase family AAA domain-containing protein 3, ATPase family, AAA domain containing 3A, FLJ10709, FLJ35514, AAA ATPase TOB3, AAA-TOB3, ATPase family AAA domain containing protein 3B, ATPase family, AAA domain containing 3B, ATPase family, AAA domain containing, member 3B, TOB3, ATD3A_HUMAN, ATAD3A/B/C.

Background: The AAA ATPase family of molecular chaperones are characterized by a highly conserved AAA motif. Composed of 200-250 residues, the AAA domain contains Walker homology sequences and imparts ATPase activity. Members of the AAA ATPase family act as DNA helicases as well as transcription factors and are thought to be involved in several cellular functions such as cell-cycle regulation, protein proteolysis, organelle biogenesis and vesicle-mediated protein transport. Mitochondrial membrane proteins ATAD3A and ATAD3B contribute to the stabilization of nucleoids which are large mitochondrial DNA (mtDNA)-protein complexes. ATAD3A/B may participate in the transformation pathway and the chemosensitivity of oligodendrogliomas. The genes encoding ATAD3A/B/C maps to human chromosome 1, which houses over 3,000 genes and is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome.

Gen-ID: 55210