PDZD2 Antikörper (AbBy Fluor® 350)

Produktnummer ABIN1400475

Dieses Anti-PDZD2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PDZD2 in IF (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für PDZD2 Antikörper (AbBy Fluor® 350) (ABIN1400475)

Target: PDZD2 (PDZ Domain Containing 2 (PDZD2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDZD2 Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-PDZD2 Antikörper (AbBy Fluor® 350)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDZK3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PDZD2

Target: PDZD2 (PDZ Domain Containing 2 (PDZD2))

Andere Bezeichnung: PDZK3

Hintergrund:

Synonyms: Activated in prostate cancer protein, AIPC, KIAA0300, Likely ortholog of rat plakophilin related armadillo repeat protein interacting PDZ protein antibody PAPIN, PDZ domain containing 2, PDZ domain containing 3, PDZ domain containing protein 2, PDZ domain containing protein 3, PDZD2, PDZK 2, PDZK2, PDZK-2, PDZK 3, PDZK3, PDZK-3, PIN1, Plakophilin related armadillo repeat protein interacting PDZ protein like, Rat plakophilin related armadillo repeat protein interacting PDZ protein like, PDZD2_HUMAN.

Background: Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. PDZK3 contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, the PDZK3 gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.

Gen-ID: 23037