FBXL21 Antikörper (AA 121-220) (FITC)

Produktnummer ABIN1399316

Der Kaninchen Polyklonal Anti-FBXL21-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, FBXL21 in Proben von Maus zu detektieren.

Kurzübersicht für FBXL21 Antikörper (AA 121-220) (FITC) (ABIN1399316)

Target: FBXL21 (F-Box and Leucine-Rich Repeat Protein 21 (FBXL21))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXL21 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-FBXL21 Antikörper (FITC)

Bindungsspezifität: AA 121-220

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FBXL21/FBL3B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FBXL21

Target: FBXL21 (F-Box and Leucine-Rich Repeat Protein 21 (FBXL21))

Andere Bezeichnung: FBXL21

Hintergrund:

Synonyms: F box and leucine rich repeat protein 21, F box and leucine rich repeat protein 3 pseudogene, F box and leucine rich repeat protein 3B, F box protein Fbl3b, F box/LRR repeat protein 21, F box/LRR repeat protein 3B, Fbl 21, FBXL 21, FBXL-21, FBL 3, FBL 3B, Fbl21, FBL3, FBL-3B, FBL 3B, FBL3B, FBXL 21, FBXL 3B, FBXL 3P, FBXL3B, FBXL3P, MGC120237, FXL21_HUMAN.

Background: FBL3B is a 434 amino acid protein encoded by the human gene FBXL21. FBL3B contains one 40 amino acid F-box region, making it a member of the F-box family. FBL3B also contains three LRR (leucine-rich) repeats. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. FBL3B is a substrate-recognition component of the SCF complex that interacts with Skp1 p19 and CUL-1. FBL3B is also associated with expression and regulation of circadian and cryptochrome proteins.

Gen-ID: 26223

Pathways: Photoperiodism