FBXO36 Antikörper (AA 1-100) (Biotin)

Produktnummer ABIN1399279

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FBXO36 in WB, ELISA, IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für FBXO36 Antikörper (AA 1-100) (Biotin) (ABIN1399279)

Target: FBXO36 (F-Box Protein 36 (FBXO36))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO36 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-FBXO36 Antikörper (Biotin)

Bindungsspezifität: AA 1-100

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FBXO6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu FBXO36

Target: FBXO36 (F-Box Protein 36 (FBXO36))

Andere Bezeichnung: FBXO36

Hintergrund:

Synonyms: F box only protein 36, F box protein 36, F-box only protein 36, Fbx 36, Fbx36, FBX36_HUMAN, FBXO 36, Fbxo36, FLJ37592, FLJ41090.

Background: FBXO36 is a 188 amino acid protein that contains one forty amino acid F-box region, making it a member of the F-box family. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-å and -catenin, for degradation by the proteasome after ubiquitination. Functioning as a component of the SCF complex, FBXO36 is thought to recognize and bind to select phosphorylated proteins, thereby promoting their ubiquitination and subsequent degradation.

Gen-ID: 130888

UniProt: Q8NEA4