Lin28A/ B (AA 75-180) Antikörper (AbBy Fluor® 350)

Produktnummer ABIN1399119

Der AbBy Fluor® 350-konjugierte Kaninchen Polyklonal anti-Lin28A/ B Antikörper (ABIN1399119) detektiert spezifisch Lin28A/ B in WB, IF (cc) und IF (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Lin28A/ B (AA 75-180) Antikörper (AbBy Fluor® 350) (ABIN1399119)

Target: Lin28A/ B

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: AbBy Fluor® 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails

Bindungsspezifität: AA 75-180

Spezifität: This antibody is produced using synthetic peptide that falls within the range of 90-120 amino acids of human Lin28A. Due to 92 % sequence similarity, this antibody may cross react with Lin28B.

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Lin28A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Lin28A/ B

Andere Bezeichnung: Lin28A/B

Hintergrund:

Synonyms: Protein lin-28 homolog A, LIN28A, Lin-28A, Zinc finger CCHC domain-containing protein 1, CSDD1, LIN28, ZCCHC1, Protein lin-28 homolog B, LIN28B, Lin-28B, CSDD2

Background: LIN-28 is a highly conserved, RNA-binding, cytoplasmic protein. It consists of a cold shock domain and retroviral-type (CCHC) zinc finger motifs that were first identified in Caenorhabditis elegans. LIN-28 controls the timing of events during embryonic development and is readily expressed in embryos, embryonic stem cells and embryonal carcinoma cells. The presence of LIN-28 persists in some adult tissues including cardiac and skeletal muscle. In differentiating myoblasts, LIN-28 increases protein synthesis efficiency and binds to the growth and differentiation factor IGF-II.

Gen-ID: 79727, 389421

UniProt: Q6ZN17