UBE2M Antikörper (AA 1-100) (AbBy Fluor® 647)
Kurzübersicht für UBE2M Antikörper (AA 1-100) (AbBy Fluor® 647) (ABIN1398762)
Target
Alle UBE2M (ube2m) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-100
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Kreuzreaktivität
- Xenopus laevis
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Homologie
- Human,Mouse,Rat,Cow,Horse
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human UBE2M
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- UBE2M (ube2m) (Ubiquitin-Conjugating Enzyme E2M (ube2m))
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Andere Bezeichnung
- UBE2M
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Hintergrund
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Synonyms: hUbc12, NEDD8 carrier protein, NEDD8 conjugating enzyme Ubc12, NEDD8 protein ligase, NEDD8-conjugating enzyme Ubc12, UBC-RS2, UBC12, UBC12_HUMAN, ube2m, ubiquitin carrier protein M, Ubiquitin conjugating enzyme E2 M, Ubiquitin-conjugating enzyme E2 M, ubiquitin-protein ligase M, yeast UBC12 homolog.
Background: Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation.
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Gen-ID
- 9040
Target
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