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UBE2A Antikörper (AA 81-152) (AbBy Fluor® 350)

This anti-UBE2A antibody (ABIN1398717) is a Rabbit Polyclonal antibody detecting UBE2A in IF (cc), IF (p). Suitable for Human.
Produktnummer ABIN1398717

Quick Overview for UBE2A Antikörper (AA 81-152) (AbBy Fluor® 350) (ABIN1398717)

Target

Alle UBE2A (ube2a) Antikörper anzeigen
UBE2A (ube2a) (Ubiquitin-Conjugating Enzyme E2A (ube2a))

Reaktivität

  • 35
  • 16
  • 5
  • 3
  • 3
  • 2
Human

Wirt

  • 35
  • 2
Kaninchen

Klonalität

  • 35
  • 2
Polyklonal

Konjugat

  • 17
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser UBE2A Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation

  • 14
  • 12
  • 12
  • 10
  • 8
  • 6
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 4
    • 2
    • 1
    • 1
    AA 81-152

    Homologie

    Human,Mouse,Rat,Cow,Chicken

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human UBE2A/RAD6

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    UBE2A (ube2a) (Ubiquitin-Conjugating Enzyme E2A (ube2a))

    Andere Bezeichnung

    UBE2A

    Hintergrund

    Synonyms: BHR6A, hHR6A, HR6A, mHR6A, RAD6 homolog A, RAD6A, RAD6B, UBC-1, UBC2, UBC6, UBCD6, UBE2A, UBE2A_HUMAN, UBE2B, Ubiquitin carrier protein A, Ubiquitin carrier protein, Ubiquitin conjugating enzyme E2 17 kDa, Ubiquitin conjugating enzyme E2 21.5 kDa, Ubiquitin conjugating enzyme E2 A, Ubiquitin protein ligase A, Ubiquitin-conjugating enzyme E2 A, Ubiquitin-conjugating enzyme E2-17 kDa, Ubiquitin-conjugating enzyme E2-21.5 kDa, Ubiquitin-protein ligase A.

    Background: The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. UBE2A (Ubiquitin-conjugating enzyme E2 A) and UBE2B (Ubiquitin-conjugating enzyme E2 B) are both Ub-conjugating enzymes that are essential to postreplication repair of UV-damaged DNA. UBE2A and UBE2B are both nuclear and cell membrane proteins that have been found to interact with Rad18.

    Gen-ID

    7319
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