HEATR3 Antikörper (AA 601-680) (AbBy Fluor® 555)

Produktnummer ABIN1398401

Der Kaninchen Polyklonal Anti-HEATR3-Antikörper wurde für IF (cc) und IF (p) validiert. Er ist geeignet, HEATR3 in Proben von Human zu detektieren.

Kurzübersicht für HEATR3 Antikörper (AA 601-680) (AbBy Fluor® 555) (ABIN1398401)

Target: HEATR3 (HEAT Repeat Containing 3 (HEATR3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HEATR3 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-HEATR3 Antikörper (AbBy Fluor® 555)

Bindungsspezifität: AA 601-680

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HEATR3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HEATR3

Target: HEATR3 (HEAT Repeat Containing 3 (HEATR3))

Andere Bezeichnung: HEATR3

Hintergrund:

Synonyms: HEAT repeat-containing protein 3, HEAT repeat containing 3, HEAT3_HUMAN, Heatr3.

Background: HEATR3 is a 680 amino acid protein existing as three alternatively spliced isoforms and containing two HEAT (Huntingtin, elongation factor 3 (EF3), protein phosphatase 2A (PP2A) and the yeast PI3-kinase Tor1) repeats. HEAT repeats form rod-like helical structures that are involved in intracellular transport. HEATR3 is encoded by a gene located on human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition.

Gen-ID: 55027

Pathways: SARS-CoV-2 Protein Interaktom