DPYS Antikörper (AA 121-220) (Biotin)

Produktnummer ABIN1398223

This anti-DPYS antibody (ABIN1398223) is a Rabbit Polyclonal antibody detecting DPYS in WB, ELISA, IHC (p), IHC (fro). Suitable for Human.

Kurzübersicht für DPYS Antikörper (AA 121-220) (Biotin) (ABIN1398223)

Target: DPYS (Dihydropyrimidinase (DPYS))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPYS Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-DPYS Antikörper (Biotin)

Bindungsspezifität: AA 121-220

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DHP/Dihydropyrimidinase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu DPYS

Target: DPYS (Dihydropyrimidinase (DPYS))

Andere Bezeichnung: Dihydropyrimidinase

Hintergrund:

Synonyms: DHP, DHPase, Dihydropyrimidinase, Dihydropyrimidine amidohydrolase, Dpys, DPYS_HUMAN, Hydantoinase.

Background: Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyzes the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate.Tissue specificity:Liver and kidney.Involvement in disease:Defects in DPYS are the cause of dihydropyrimidinase deficiency (DHPD). DHPD is an autosomal recessive disorder characterized by dihydropyrimidinuria and associated with a variable clinical phenotype: epileptic or convulsive attacks, dysmorphic features and severe developmental delay, and congenital microvillous atrophy.

Gen-ID: 1807