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DIRC2 Antikörper (AA 51-150) (Biotin)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DIRC2 in WB, ELISA, IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Human und Ratte.
Produktnummer ABIN1398169

Kurzübersicht für DIRC2 Antikörper (AA 51-150) (Biotin) (ABIN1398169)

Target

Alle DIRC2 Antikörper anzeigen
DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))

Reaktivität

  • 25
  • 15
  • 3
  • 2
  • 2
  • 2
  • 1
Human, Ratte

Wirt

  • 25
Kaninchen

Klonalität

  • 25
Polyklonal

Konjugat

  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DIRC2 Antikörper ist konjugiert mit Biotin

Applikation

  • 25
  • 13
  • 13
  • 10
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 14
    • 7
    • 1
    • 1
    • 1
    • 1
    AA 51-150

    Kreuzreaktivität

    Human, Ratte

    Homologie

    Mouse,Dog,Sheep,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human DIRC2

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))

    Andere Bezeichnung

    DIRC2

    Hintergrund

    Synonyms: Disrupted in renal carcinoma protein 2, DIRC 2, Disrupted in renal cancer protein 2, Disrupted in renal carcinoma 2, FLJ14784, NP_116228, RCC 4, RCC4, Renal cell carcinoma 4, DIRC2_HUMAN.

    Background: Belonging to the major facilitator superfamily, DIRC2 (disrupted in renal carcinoma protein 2) is a 478 amino acid multi-pass membrane protein that is primarily expressed in kidney proximal tubular cells. The genes encoding DIRC2 and DIRC3 are located at a translocation breakpoint which occurs frequently in individuals affected by familial renal cell carcinoma. Fusion transcripts that result from these translocations may affect normal protein function. This evidence suggests that, due to its chromosomal location, deregulation of the DIRC2 gene may cause haploinsufficiency and therefore result in the onset of tumor growth. There are two isoforms of DIRC2 which are produced as a result of alternative splicing events.

    Gen-ID

    84925
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