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NSG1 Antikörper (AA 1-100) (Biotin)

D4S234E Reaktivität: Maus, Affe WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1398007
  • Target Alle NSG1 (D4S234E) Antikörper anzeigen
    NSG1 (D4S234E) (Neuron-Specific Protein Family Member 1 (D4S234E))
    Bindungsspezifität
    • 14
    • 10
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reaktivität
    • 30
    • 26
    • 15
    • 12
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Maus, Affe
    Wirt
    • 41
    • 3
    • 1
    Kaninchen
    Klonalität
    • 42
    • 3
    Polyklonal
    Konjugat
    • 20
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NSG1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 45
    • 28
    • 13
    • 13
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Affe, Maus
    Homologie
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NEEP21
    Isotyp
    IgG
    Top Product
    Discover our top product D4S234E Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    NSG1 (D4S234E) (Neuron-Specific Protein Family Member 1 (D4S234E))
    Andere Bezeichnung
    NEEP21 (D4S234E Produkte)
    Synonyme
    D4S234 antikoerper, D4S234E antikoerper, NEEP21 antikoerper, P21 antikoerper, Neep21 antikoerper, m234 antikoerper, p21 antikoerper, Bsmrb antikoerper, PEP1 antikoerper, neuronal vesicle trafficking associated 1 antikoerper, neuron specific gene family member 1 antikoerper, NSG1 antikoerper, Nsg1 antikoerper
    Hintergrund

    Synonyms: neuron-enriched endosomal 21 kDa protein, NSG1_HUMAN.

    Background: NEEP21, also known as Brain neuron cytoplasmic protein 1, NSG1 (neuron-specific proteins family member 1), P21 or D4S234E, is a single pass type II membrane protein belonging to the NSG family. It is highly expressed during neuronal maturation but its expression is downregulated in adult tissues. NEEP21 predominantly localizes to Rab 4-positive early endosomes in the somatodendritic neuronal compartment and is essential for proper receptor sorting and recycling in neurons. It associates with GRIP1 and GluR-2 and mediates the surface expression of GluR-2. When this interaction is interrupted, GluR-2 accumulates in early endosomes and leads to changes in evoked synaptic current properties. In addition, NEEP21 forms a complex with the SNARE protein, Syntaxin 13 (also known as Syntaxin 12), and participates in the recycling of transferrin receptors (TFRs) and NTR2 (neurotensin receptor 2).

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