KCNJ10 Antikörper (Biotin)

Produktnummer ABIN1396080

Dieses Anti-KCNJ10-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KCNJ10 in WB und IHC (p). Geeignet für Human, Ratte und Maus.

Kurzübersicht für KCNJ10 Antikörper (Biotin) (ABIN1396080)

Target: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNJ10 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-KCNJ10 Antikörper (Biotin)

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Kir4.1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: (1:100-1000), IHC-P: (1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4 °C for 12 months.

Haltbarkeit: 12 months

Details zu KCNJ10

Target: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Andere Bezeichnung: Kir4.1

Hintergrund: The KIR (for inwardly rectifying potassium channel) family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. KIR4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. KIR4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human KIR4.1 maps to chromosome 1. KIR4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human KIR4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and KIR4.2 may play a role in the pathogenesis of Downs syndrome. KIR5.1 forms functional channels only by coexpression with either KIR4.1 or KIR4.2 in the kidney and pancreas. The gene encoding human KIR5.1 maps to chromosome 17.
Synonyms: ATP dependent inwardly rectying potassium channel Kir4.1, ATP sensitive inward rectier potassium channel 10, ATP-dependent inwardly rectying potassium channel Kir4.1, ATP-sensitive inward rectier potassium channel 10, BIRK10, Glial ATP dependent inwardly rectying potassium channel KIR4.1, Inward rectier K+ channel Kir1.2, Inward rectier K+ channel KIR1.2, Inwardly rectying potassium channel Kir1.2, inwardly rectying subfamily J member 10, KCNJ 10, Kcnj10, KCNJ13 PEN, KIR1.2, KIR4.1, Potassium channel, Potassium channel inwardly rectying subfamily J member 10, Potassium inwardly rectying channel subfamily J member 10, SESAME, IRK10_HUMAN.
Subcellular locations: Extracellular

Gen-ID: 3766

Pathways: Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity