KCNT2 Antikörper (AA 51-150) (AbBy Fluor® 647)

Produktnummer ABIN1395606

Der AbBy Fluor® 647-konjugierte Kaninchen Polyklonal anti-KCNT2 Antikörper (ABIN1395606) detektiert spezifisch KCNT2 in IF (cc) und IF (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für KCNT2 Antikörper (AA 51-150) (AbBy Fluor® 647) (ABIN1395606)

Target: KCNT2 (Potassium Channel, Subfamily T, Member 2 (KCNT2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNT2 Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-KCNT2 Antikörper (AbBy Fluor® 647)

Bindungsspezifität: AA 51-150

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KCNT2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu KCNT2

Target: KCNT2 (Potassium Channel, Subfamily T, Member 2 (KCNT2))

Andere Bezeichnung: KCNT2

Hintergrund:

Synonyms: KCa4.2, Potassium channel, subfamily T, member 2, Sequence like an intermediate conductance potassium channel subunit, SLICK, SLO2.1, Sodium and chloride activated ATP sensitive potassium channel, Sodium and chloride activated ATP sensitive potassium channel Slo2.1, KCNT2_HUMAN.

Background: Voltage-gated K+ channels in the plasma membrane are important regulators of electrical signaling, controlling the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. KCNT2 is a 1,135 amino acid multi-pass transmembrane protein belonging to the potassium channel family (calcium-activated subfamily) of proteins. KCNT2 produces rapidly activating outward rectifier potassium currents in reponse to high intracellular sodium and chloride levels. Its channel activity is inhibited by ATP, inhalation anesthetics, such as isoflourane, and upon stimulation of G-protein coupled receptors, such as mAChR M1 and GluR-1. There are four isoforms of KCNT2 that are produced as a result of alternative splicing events.