DLGAP4 Antikörper (AA 261-370) (FITC)

Produktnummer ABIN1395398

Der Kaninchen Polyklonal anti-DLGAP4 Antikörper wird verwendet zum Nachweis von DLGAP4 in Proben von Maus und Ratte. Er wurde validiert für WB, IF (cc) und IF (p).

Kurzübersicht für DLGAP4 Antikörper (AA 261-370) (FITC) (ABIN1395398)

Target: DLGAP4 (Discs, Large (Drosophila) Homolog-Associated Protein 4 (DLGAP4))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLGAP4 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-DLGAP4 Antikörper (FITC)

Bindungsspezifität: AA 261-370

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SAPAP4/DLGAP4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DLGAP4

Target: DLGAP4 (Discs, Large (Drosophila) Homolog-Associated Protein 4 (DLGAP4))

Andere Bezeichnung: SAPAP4/DLGAP4

Hintergrund:

Synonyms: DAP 4, DAP-4, DAP4, Discs, large Drosophila homolog associated protein 4, Disks large associated protein 4, Disks large-associated protein 4, DLGAP4, DLGP4_HUMAN, DLP4, PSD 95/SAP90 binding protein 4, PSD-95/SAP90-binding protein 4, RP5-977B1.6, SAP90/PSD-95-associated protein 4, SAPAP 4, SAPAP-4, SAPAP4.

Background: A guanylate kinase is a phosphotransferase that produces ADP and GDP from the substrates ATP and GMP. SAPAP4 is a 992 amino acid protein that likely localizes to the postsynaptic membrane of neurons to enhance neuronal signaling. SAPAP4 could act as a signaling molecule which interacts with the human genes DLG1 and DLG4/PSD-95. The gene encoding SAPAP4, DLGAP4, maps to human chromosome 20. Comprising approximately 2 % of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.