DLGAP2 Antikörper (AA 251-360) (Biotin)

Produktnummer ABIN1395391

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DLGAP2 in WB, ELISA, IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für DLGAP2 Antikörper (AA 251-360) (Biotin) (ABIN1395391)

Target: DLGAP2 (Discs, Large (Drosophila) Homolog-Associated Protein 2 (DLGAP2))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLGAP2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-DLGAP2 Antikörper (Biotin)

Bindungsspezifität: AA 251-360

Kreuzreaktivität: Human, Ratte

Homologie: Mouse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SAPAP2/DLGAP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu DLGAP2

Target: DLGAP2 (Discs, Large (Drosophila) Homolog-Associated Protein 2 (DLGAP2))

Andere Bezeichnung: SAPAP2/DLGAP2

Hintergrund:

Synonyms: DAP-2, DAP2, Discs large Drosophila homolog associated protein 2, Discs large homolog associated protein 2, Disks large-associated protein 2, Dlgap2, DLGP2_HUMAN, PSD-95/SAP90-binding protein 2, SAP90/PSD-95-associated protein 2, SAPAP2, hide.

Background: A guanylate kinase is a phosphotransferase that produces ADP and GDP from the substrates ATP and GMP. SAPAP2, also known as DAP-2 (Disks large-associated protein 2) and PSD-95/SAP90-binding protein 2, is a 1054 amino acid protein that localizes to the postsynaptic membrane of neuronal cells of the brain and kidney. SAPAP2 likely acts as a signaling molecule which interacts with the human genes DLG1 and DLG4/PSD-95. The gene encoding SAPAP2, DLGAP2, maps to human chromosome 8. Consisting of nearly 146 million base pairs, chromosome 8 encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8.