NTSR2 Antikörper (AA 151-250) (AbBy Fluor® 555)
Kurzübersicht für NTSR2 Antikörper (AA 151-250) (AbBy Fluor® 555) (ABIN1394597)
Target
Alle NTSR2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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    - 
                                            Bindungsspezifität
- AA 151-250
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                                            Kreuzreaktivität
- Maus
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                                            Homologie
- Human,Rat,Dog,Cow,Sheep,Rabbit
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                                            Aufreinigung
- Purified by Protein A.
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                                            Immunogen
- KLH conjugated synthetic peptide derived from human Neurotensin Receptor 2
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                                            Isotyp
- IgG
 
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- 
    - 
                                            Applikationshinweise
- 
                        IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 1 μg/μL
- 
                                            Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 
                                            Konservierungsmittel
- ProClin
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                                            Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 
                                            Lagerung
- -20 °C
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                                            Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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                                            Haltbarkeit
- 12 months
 
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    - NTSR2 (Neurotensin Receptor 2 (NTSR2))
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                                            Andere Bezeichnung
- Neurotensin Receptor 2
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                                            Hintergrund
- 
                        Synonyms: Levocabastine sensitive neurotensin receptor, Levocabastine-sensitive neurotensin receptor, Neurotensin receptor type 2, NT R 2, NT-R-2, NTR2, NTR2 receptor, NTR2_HUMAN, Ntsr2. Background: Neurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2 (NTS2 receptor, levocabastine-sensitive neurotensin receptor), and the type I receptor NTR3 (NTS3 receptor, sortilin-1, Gp95). NT has a wide distribution in regions of the brain and in peripheral tissues where NT receptors can contribute to hypotension, hyperglycemia, hypothermia, antinociception and regulation of intestinal motility and secretion. HL-60 cells express NTR1, which can couple to Gq, Gi/o, or Gs. Alternative splicing of rat NTR2 can generate a 5-transmembrane domain variant isoform that is co-expressed with the full-length NTR2 throughout the brain and spinal cord. NTR3 activation in the murine microglial cell line N11 induces MIP-2, MCP-1, IL-1beta and TNF?in an ERK1/2 and Akt kinase-dependent manner. 
 Target
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